Calorie restriction and calorie dilution have different impacts on body fat, metabolism, behavior and hypothalamic gene expression
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ABSTRACT: Caloric restriction is a robust intervention to increase life span. Giving less food (CR), or allowing free access to diluted diet with indigestible components (CD) are two methods to impose restriction. CD does not generate the same lifespan effect as CR. We compared responses of C57BL/6 mice to equivalent levels of CR and CD. Our study calorie restriction and calorie two restriction methods different effect on hypothamic gene expression pattern, RNA-seq was performed using hypothalamus of mice with 2 methods treatment as well as control group.
ORGANISM(S): Mus musculus
PROVIDER: GSE200820 | GEO | 2022/05/17
REPOSITORIES: GEO
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