ABSTRACT: A Saccharomyces cerevisiae population was cultured for many generations under conditions to which it is not optimally adapted. These experiments were designed to investigate adaptive evolution under natural selection. This study is described in more detail in Ferea TL, et al. 1999. Proc Natl Acad Sci USA 96:9721-6 Keywords: other
Project description:A Saccharomyces cerevisiae population was cultured for many generations under conditions to which it is not optimally adapted. These experiments were designed to investigate adaptive evolution under natural selection. This study is described in more detail in Ferea TL, et al. 1999. Proc Natl Acad Sci USA 96:9721-6
Project description:This experiment set contains the arrays referenced in Ferea, TL, et al. titled "Systematic changes in gene expression patterns following adaptive evolution in yeast"(Proc Natl Acad Sci USA 1999 96(17):9721-6). A Saccharomyces cerevisiae population was cultured for many generations under conditions to which it is not optimally adapted. These experiments were designed to investigate adaptive evolution under natural selection.
Project description:Identification of hair cycle-associated genes from time-course gene expression profile data by using replicate variance. Proc. Natl. Acad. Sci. USA. (2004) Keywords: time-course
Project description:This is a training data set for destructin-1 protease digestion of a synthetic peptide library for substrate specificity profiling. Data is related to the following publication:
O'Donoghue AJ, Knudsen GM, Beekman C, Perry JA, Johnson AD, DeRisi JL, Craik
CS, Bennett RJ. "Destructin-1 is a collagen-degrading endopeptidase secreted by
Pseudogymnoascus destructans, the causative agent of white-nose syndrome." Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):7478-83. doi: 10.1073/pnas.1507082112.
Epub 2015 May 5. Erratum in: Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):E3152.
PMCID: PMC4475985.
Project description:To detect somatic copy number alterations in APC mutant tumors, we analyzed intestinal tumors from heterozygous ApcΔ716 mice, in which polyposis initiates upon loss of heterozygosity without losing the mutant allele (Proc Natl Acad Sci U S A. 1995 May 9;92(10):4482-6).
Project description:Series of 6 repetitions of hybridization of treatment (psbs) and control (WT) each. Comparison of the Arabidopsis psbs mutant lacking Photosystem I protein PSII-S versus WT. X.P. Li et al., Proc Natl Acad Sci U S A 99 (2002), pp. 15222-15227 Keywords: repeat sample
Project description:The ultraconserved RNA TUC338 is expressed in hepatocellular cancer and can modulate cell proliferation. Details are provided in Braconi et al,Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):786-91. In this analysis, we knocked down TUC338 in HepG2 cells and analyzed gene expression.
Project description:Identification of hair cycle-associated genes from time-course gene expression profile data by using replicate variance. Proc. Natl. Acad. Sci. USA. (2004)
Project description:Whole transcriptome expression analysis of INA6 cells on Affymetrix Human Tiling 1.0 array set. IL-6 has been withdrawn for 13 hours which initiates apoptosis. Expression data were processed with MAT (Johnson et al., "Model-based analysis of tiling-arrays for ChIP-chip." Proc Natl Acad Sci USA, 103:12457-62, 2006.).
Project description:Whole transcriptome expression analysis of HFF cells on Affymetrix Human Tiling 1.0 array set. Cells were synchronised by serum starvation and transcriptome-wide expression in G1 phase. Expression data were processed with MAT (Johnson et al., "Model-based analysis of tiling-arrays for ChIP-chip." Proc Natl Acad Sci USA, 103:12457-62, 2006.).