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Gene expression profiles of effector T cells induced by mTOR inhibition

ABSTRACT: To further develop our gene expression approach to treatment of autoimmunity, we have employed whole genome microarray expression profiling as a discovery platform to identify genes differentially expressed upon immunosuppressor treatment responsible for inhibition of T cell effector functions. Human CD4+CD25- cells from healthy donors were pretreated or not with rapamycin and stimulated with anti-CD3 and anti-CD28 for 12h.

ORGANISM(S): Homo sapiens

PROVIDER: GSE29606 | GEO | 2012/09/05

SECONDARY ACCESSION(S): PRJNA153817

REPOSITORIES: GEO

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Gene expression profiles of effector T cells induced by mTOR inhibition

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