Polycomb Cbx orthologs mediate the balance between Hematopoietic Stem Cell self-renewal and differentiation
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ABSTRACT: By genome-wide ChIP-seq analyses we show that Cbx7 and Cbx8 share ~95% of their targets in bone marrow cells. Cbx7 and Cbx8 have only ~200 targets that are not overlapping between the two proteins. These distinct Cbx7 and Cbx8 targets show reciprocal expression patterns along hematopoietic differentiation.
ORGANISM(S): Mus musculus
PROVIDER: GSE36658 | GEO | 2012/12/21
SECONDARY ACCESSION(S): PRJNA153665
REPOSITORIES: GEO
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