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HTERT effects in CD8 T Lymphocytes HD1

ABSTRACT: Using CD8+ T lymphocyte clones over-expressing telomerase weinvestigated the molecular mechanisms that regulate T cell proliferation. Transduction and subcloning procedures were performed on CD8 + naive T-cell clones isolated from two different healthy individuals aged between 30 to 35 years (HD1 and HD2). T-cell cloneswere transduced to express hTERT/GFP or GFP alone. HD2 was profiled on U133Plus 2.0 and submitted as a separate GEO series. Keywords: Cell Line Comparison.

ORGANISM(S): Homo sapiens

PROVIDER: GSE5142 | GEO | 2006/06/24

SECONDARY ACCESSION(S): PRJNA96655

REPOSITORIES: GEO

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