Genomics

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3 cases of renal cell carcinomas with TFEB amplification


ABSTRACT: We report here 3 cases of a very rare entity of renal cell carcinomas (RCCs) that present an amplification of TFEB gene. This amplification, as well as translocation t(6;11) involving TFEB and MALAT1, leads to un overexpression of TFEB protein and seems to be a pejorative prognosis factor among TFEB RCCs

ORGANISM(S): Homo sapiens

PROVIDER: GSE73979 | GEO | 2015/10/14

SECONDARY ACCESSION(S): PRJNA298640

REPOSITORIES: GEO

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