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Schizophrenia Plasma Metabolome Analysis

ABSTRACT: Metabolomics analysis of plasma collected from patients with schizophrenia and non-psychiatric control subjects.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: David Gonzalez

PROVIDER: MSV000086975 | MassIVE | Tue Mar 02 14:09:00 GMT 2021

REPOSITORIES: MassIVE

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Publications

Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.

Zhang Yueyi Y Wang Shan S Dai Xuan X Liu Tianyuan T Liu Yage Y Shi Hanfen H Yin Jiyuan J Xu Tianshu T Zhang Yanfei Y Zhao Dandan D Sukhorukov Vasily V Orekhov Alexander N AN Gao Sihua S Wang Lili L Zhang Dongwei D

Journal of ethnopharmacology 20230423

<h4>Ethnopharmacological relevance</h4>Simiao San (SmS), a famous traditional Chinese formula, is clinically used to treat patients with hyperuricemia (HUA). However, its mechanism of action on lowering uric acid (UA) and inhibiting inflammation still deserves further investigation.<h4>Aim of the study</h4>To examine the effect and its possible underlying mechanism of SmS on UA metabolism and kidney injury in HUA mouse.<h4>Materials and methods</h4>The HUA mouse model was constructed with the co ...[more]

PMID: 37098372

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