Proteomics

Dataset Information

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Schizophrenia Plasma Metabolome Analysis


ABSTRACT: Metabolomics analysis of plasma collected from patients with schizophrenia and non-psychiatric control subjects.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: David Gonzalez  

PROVIDER: MSV000086975 | MassIVE | Tue Mar 02 14:09:00 GMT 2021

REPOSITORIES: MassIVE

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Publications

Multi-omics of human plasma reveals molecular features of dysregulated inflammation and accelerated aging in schizophrenia.

Campeau Anaamika A   Mills Robert H RH   Stevens Toer T   Rossitto Leigh-Ana LA   Meehan Michael M   Dorrestein Pieter P   Daly Rebecca R   Nguyen Tanya T TT   Gonzalez David J DJ   Jeste Dilip V DV   Hook Vivian V  

Molecular psychiatry 20211105 2


Schizophrenia is a devastating psychiatric illness that detrimentally affects a significant portion of the worldwide population. Aging of schizophrenia patients is associated with reduced longevity, but the potential biological factors associated with aging in this population have not yet been investigated in a global manner. To address this gap in knowledge, the present study assesses proteomics and metabolomics profiles in the plasma of subjects afflicted with schizophrenia compared to non-psy  ...[more]

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