Proteomics

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Protemic analysis of human hippocampus shows differential protein expression in the different hippocampal subfields

ABSTRACT: Not available

INSTRUMENT(S): Bruker Daltonics HCT Series, instrument model

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Brain

SUBMITTER: WeiQiang Chen  

PROVIDER: PRD000644 | Pride | 2013-04-24

REPOSITORIES: Pride

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PRIDE_Exp_Complete_Ac_21593.pride.mgf.gz Mgf
PRIDE_Exp_Complete_Ac_21593.pride.mztab.gz Mztab
PRIDE_Exp_Complete_Ac_21593.xml.gz Xml
PRIDE_Exp_Complete_Ac_21594.pride.mgf.gz Mgf
PRIDE_Exp_Complete_Ac_21594.pride.mztab.gz Mztab
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Proteomic analysis of human hippocampus shows differential protein expression in the different hippocampal subfields.

Föcking Melanie M   Chen Wei-Qiang WQ   Dicker Patrick P   Dunn Michael J MJ   Lubec Gert G   Cotter David R DR  

Proteomics 20120801 15-16

In the current investigation, we aimed to characterize the differential protein expression in each of the hippocampal subregions in healthy control samples (n = 20). We used laser-assisted microdissection and difference in-gel electrophoresis to enrich for these tissues and to compare protein profiles. Image analysis was carried out using Progenesis SameSpots. Samples with a false discovery rate smaller than 5%, a p-value of < 0.01, and an expression of at least ± 1.2 were considered significant  ...[more]

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