Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Escherichia Coli
SUBMITTER: Willy Bienvenut
LAB HEAD: Willy V Bienvenut
PROVIDER: PXD001979 | Pride | 2015-07-21
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
10062011_ALP_060611_Ech1-1.dat | Other | |||
10062011_ALP_060611_Ech1-2.dat | Other | |||
10062011_ALP_060611_Ech1-3.dat | Other | |||
10062011_ALP_060611_Ech1-4.dat | Other | |||
10062011_ALP_060611_Ech11-1.raw | Raw |
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Proteomics 20150701 14
A proteome wide analysis was performed in Escherichia coli to identify the impact on protein N-termini of actinonin, an antibiotic specifically inhibiting peptide deformylase (PDF). A strategy and tool suite (SILProNaQ) was employed to provide large-scale quantitation of N-terminal modifications. In control conditions, more than 1000 unique N-termini were identified with 56% showing initiator methionine removal. Additional modifications corresponded to partial or complete Nα-acetylation (10%) an ...[more]