Dataset Information

Shotgun proteomics analysis of single human tubules

ABSTRACT: We analyzed microdissected single tubules from human with shotgun proteomics.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Kidney

SUBMITTER: Markus Rinschen

LAB HEAD: Markus Rinschen

PROVIDER: PXD006897 | Pride | 2018-06-28

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	20170426_Q2_JK_ColID_340_ProjID_541_Benzing_1.index	Other
	20170426_Q2_JK_ColID_340_ProjID_541_Benzing_1.raw	Raw
	20170426_Q2_JK_ColID_340_ProjID_541_Benzing_10.index	Other
	20170426_Q2_JK_ColID_340_ProjID_541_Benzing_10.raw	Raw
	20170426_Q2_JK_ColID_340_ProjID_541_Benzing_11.index	Other

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Publications

Single-nephron proteomes connect morphology and function in proteinuric kidney disease.

Höhne Martin M Frese Christian K CK Grahammer Florian F Dafinger Claudia C Ciarimboli Giuliano G Butt Linus L Binz Julia J Hackl Matthias J MJ Rahmatollahi Mahdieh M Kann Martin M Schneider Simon S Altintas Mehmet M MM Schermer Bernhard B Reinheckel Thomas T Göbel Heike H Reiser Jochen J Huber Tobias B TB Kramann Rafael R Seeger-Nukpezah Tamina T Liebau Max C MC Beck Bodo B BB Benzing Thomas T Beyer Andreas A Rinschen Markus M MM

Kidney international 20180309 6

In diseases of many parenchymatous organs, heterogeneous deterioration of individual functional units determines the clinical prognosis. However, the molecular characterization at the level of such individual subunits remains a technological challenge that needs to be addressed in order to better understand pathological mechanisms. Proteinuric glomerular kidney diseases are frequent and assorted diseases affecting a fraction of glomeruli and their draining tubules to variable extents, and for wh ...[more]

PMID: 29530281

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