Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Primary Cell Line Cell, Primary Neuron, Cell Culture
SUBMITTER: Ashfaqul Hoque
LAB HEAD: Associate Professor Heung-Chin Cheng
PROVIDER: PXD008353 | Pride | 2019-03-07
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
140613_Ash_Batch6_15min.pdResult | Other | |||
140613_Ash_Batch6_15min.raw | Raw | |||
140613_Ash_Batch6_240min.pdResult | Other | |||
140613_Ash_Batch6_240min.raw | Raw | |||
140613_Ash_Batch6_30min.pdResult | Other |
Items per page: 1 - 5 of 74 |
Cell death & disease 20190301 3
Excitotoxicity, caused by overstimulation or dysregulation of ionotropic glutamate receptors (iGluRs), is a pathological process directing neuronal death in many neurological disorders. The aberrantly stimulated iGluRs direct massive influx of calcium ions into the affected neurons, leading to changes in expression and phosphorylation of specific proteins to modulate their functions and direct their participation in the signalling pathways that induce excitotoxic neuronal death. To define these ...[more]