Proteomics

Dataset Information

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Shotgun proteomic profiling of skin mucus common carp (Cyprinus carpio)

ABSTRACT: Ichthyophthirius multifiliis is a ciliated protozoan parasite recognized as one of the most pathogenic diseases of wild and cultured freshwater fish. Fish skin mucus plays a significant role against invading pathogens. However, the protein-based modulation against infection with I. multifiliis, of host fish at this barrier is unknown. The aim of this study was to investigate the modulation of the skin mucus after infection with I. multifiliis using quantitative proteomics to provide insights into the post-transcriptional and post-translational regulation of skin mucus proteins. Thus, we investigated the skin mucus proteome of common carp (Cyprinus carpio) using a shotgun proteomic approach at days 1 and 9 after I. multifiliis exposure.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Cyprinus Carpio (common Carp)

TISSUE(S): Skin Mucus

SUBMITTER: Gokhlesh Kumar  

LAB HEAD: Dr. Mona Saleh

PROVIDER: PXD011148 | Pride | 2018-11-14

REPOSITORIES: Pride

Json Xml

Dataset's files

Source:
Action DRS
IDA_Control1.mgf Mgf
IDA_Control1.wiff Wiff
IDA_Control1.wiff.scan Wiff
IDA_Control1.xml Xml
IDA_Control2.mgf Mgf
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Publications

Quantitative shotgun proteomics distinguishes wound-healing biomarker signatures in common carp skin mucus in response to Ichthyophthirius multifiliis.

Saleh Mona M   Kumar Gokhlesh G   Abdel-Baki Abdel-Azeem AA   Dkhil Mohamed A MA   El-Matbouli Mansour M   Al-Quraishy Saleh S  

Veterinary research 20180420 1

Ichthyophthirius multifiliis is a ciliated protozoan parasite recognized as one of the most pathogenic diseases of wild and cultured freshwater fish. Fish skin mucus plays a significant role against invading pathogens. However, the protein-based modulation against infection with I. multifiliis, of host fish at this barrier is unknown. Thus, we investigated the skin mucus proteome of common carp using a shotgun proteomic approach at days 1 and 9 after I. multifiliis exposure. We identified 25 dif  ...[more]

PMID: 29678203

Publication: 1/2

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