Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Lymph Node
SUBMITTER: Matthew Monroe
LAB HEAD: Heather Smallwood
PROVIDER: PXD013690 | Pride | 2021-09-08
REPOSITORIES: Pride
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PLoS pathogens 20201026 10
Infection with the influenza virus triggers an innate immune response that initiates the adaptive response to halt viral replication and spread. However, the metabolic response fueling the molecular mechanisms underlying changes in innate immune cell homeostasis remain undefined. Although influenza increases parasitized cell metabolism, it does not productively replicate in dendritic cells. To dissect these mechanisms, we compared the metabolism of dendritic cells to that of those infected with ...[more]