Proteomics

Dataset Information

0

Thermal proteome profiling in Clostridium saccharolyticum

ABSTRACT: We used thermal proteome profiling (TPP) to study the thermostability of Clostridium saccharolyticum in the presence of duloxetine.

INSTRUMENT(S): Q Exactive

ORGANISM(S): [clostridium] Saccharolyticum

SUBMITTER: Andre Mateus  

LAB HEAD: Kiran Patil

PROVIDER: PXD016064 | Pride | 2021-07-01

REPOSITORIES: Pride

Json Xml

Dataset's files

Source:
Action DRS
Bert_S1645_AM_2DTPP_Ecoli_Csacch_lysate_duloxetine_T1T2_n1_R1_F1.raw Raw
Bert_S1645_AM_2DTPP_Ecoli_Csacch_lysate_duloxetine_T1T2_n1_R1_F2.raw Raw
Bert_S1645_AM_2DTPP_Ecoli_Csacch_lysate_duloxetine_T1T2_n1_R1_F3.raw Raw
Bert_S1645_AM_2DTPP_Ecoli_Csacch_lysate_duloxetine_T1T2_n1_R1_F4.raw Raw
Bert_S1645_AM_2DTPP_Ecoli_Csacch_lysate_duloxetine_T1T2_n1_R1_F5.raw Raw
Items per page:
1 - 5 of 66
altmetric image

Publications

Bacteria in the gut can modulate the availability and efficacy of therapeutic drugs. However, the systematic mapping of the interactions between drugs and bacteria has only started recently<sup>1</sup> and the main underlying mechanism proposed is the chemical transformation of drugs by microorganisms (biotransformation). Here we investigated the depletion of 15 structurally diverse drugs by 25 representative strains of gut bacteria. This revealed 70 bacteria-drug interactions, 29 of which had n  ...[more]

Similar Datasets

Proteomics Thermal proteome profiling in Escherichia coli
2021-07-01 | PXD016062 | Pride
Proteomics Thermal proteome profiling of phosphorylated proteoforms
2021-01-04 | PXD015993 | Pride
Proteomics Thermal proteome profiling in Escherichia coli
2018-07-09 | PXD009495 | Pride
Proteomics Thermal proteome profiling of yeast phosphodeficient mutants
2021-09-17 | PXD017929 | Pride
Proteomics Thermal proteome profiling of anti-HEV compound
2021-01-04 | PXD014485 | Pride
Proteomics Thermal proteome profiling of ticagrelor in Staphylococcus aureus
2024-01-26 | PXD036188 | Pride
Proteomics Thermal proteome profiling of darobactin in Escherichia coli
2019-10-29 | PXD013319 | Pride
Proteomics Thermal proteome profiling in of CA-074me
2020-02-07 | PXD016086 | Pride
Proteomics Thermal proteome profiling SCH79797 and trimethoprim in Escherichia coli
2020-05-19 | PXD013673 | Pride
Proteomics,Multiomics Thermal proteome profiling of nlpI mutants in Escherichia coli
2020-02-25 | PXD016819 | Pride