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Identification of Eimeria sporozoite antigens of common immunogenicity

ABSTRACT: Whole sporozoite proteins of Eimeria acervulina were prepared and analyzed by 2-dimensional gel electrophoresis (2-DE) followed by Western blotting using immune sera specific to E. tenella, E. acervulina, or E. necatrix.

INSTRUMENT(S): ultraflex

ORGANISM(S): Eimeria Acervulina

SUBMITTER: LIHENG LIU

LAB HEAD: Li-Heng Liu

PROVIDER: PXD016418 | Pride | 2020-05-27

REPOSITORIES: Pride

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Immunoproteomic and mass spectrometric analysis of Eimeria acervulina antigens recognized by antisera from chickens infected with E. acervulina, E. tenella or E. necatrix.

Liu Jin J Tuo Wenbin W Wu Xiangdong X Xiong Jiaming J Yu Enchao E Yin Chao C Ma Zhiwu Z Liu Liheng L

Parasites & vectors 20200221 1

<h4>Background</h4>Coccidiosis is caused by Eimeria spp. and can result in severe economic losses to the global poultry industry. Due to anticoccidial drug resistance rapidly developing in the parasites and drug residues in poultry products, efficacious and safe alternative coccidia control measures are needed. The objective of the present study was to identify common protective antigens which may be used as vaccine candidates in the development of subunit, multivalent, cross-protective vaccines ...[more]

PMID: 32085718

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