Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: MODEL1109130000MODEL1909260003MODEL1909260004MODEL1703310000MODEL1909260005MODEL1909260006MODEL1311110000MODEL1311110001
INSTRUMENT(S): Q-Tof Ultima, LTQ Orbitrap XL
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Cell Culture, Fibroblast
SUBMITTER: Jörg Klug
LAB HEAD: Prof. Dr. Andreas Meinhardt
PROVIDER: PXD020449 | Pride | 2021-01-27
REPOSITORIES: Pride
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The Journal of biological chemistry 20090120 12
Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine that has been implicated in the pathogenesis of inflammatory disorders such as infection, sepsis, and autoimmune disease. MIF exists preformed in cytoplasmic pools and exhibits an intrinsic tautomerase and oxidoreductase activity. MIF levels are elevated in the serum of animals and patients with infection or different inflammatory disorders. To elucidate how MIF actions are controlled, we searched for endogenous MIF-interacti ...[more]