Dataset Information

Fibrinogen-like protein 1 is a novel biomarker for predicting disease activity and prognosis of rheumatoid arthritis

ABSTRACT: A total of 762 proteins were identified from 35 pooled rheumatoid arthritis (RA) patients with moderate to high disease activity and 60 pooled healthy serum samples. Among them, 142 proteins including 68 up-regulation and 74 down-regulation were identified in RA compared to healthy subjects.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Serum

SUBMITTER: zhou wei

LAB HEAD: Wei Zhou

PROVIDER: PXD021689 | Pride | 2021-09-09

REPOSITORIES: Pride

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Publications

Fibrinogen-Like Protein 1 Is a Novel Biomarker for Predicting Disease Activity and Prognosis of Rheumatoid Arthritis.

Liu Shijia S Guo Yunke Y Lu Lu L Lu Jiawei J Ke Mengying M Xu Tingting T Lu Yan Y Chen Wenjun W Wang Jue J Kong Deshun D Shen Qiuxiang Q Zhu Youjuan Y Tan WenFeng W Ji Wei W Zhou Wei W

Frontiers in immunology 20201006

Rheumatoid arthritis (RA), afflicting over 1% of the population, is an inflammatory joint disease leading to cartilage damage and ultimately impaired joint function. Disease-modifying anti-rheumatic drugs are considered as the first-line treatment to inhibit the progression of RA, and the treatment depends on the disease status assessment. The disease activity score 28 as clinical gold standard is extensively used for RA assessment, but it has the limitations of delayed assessment and the need f ...[more]

PMID: 33123164

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