Proteomics

Dataset Information

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A proteomic approach to understand the clinical significance of acute myeloid leukemia-derived extracellular vesicles reflecting essential characteristics of leukemia


ABSTRACT: Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults and its overall incidence has been increasing gradually over the years. Extracellular vesicles (EVs) are known to express the properties of their parental cells, including proteins, RNAs, and DNAs. As EVs are representative of their parental tissues, they are excellent tools for understanding how cancer cells adapt to their environment. Proteomic analysis is a useful technique in cancer research that can be both quantitative and qualitative when determining the interrelationships between proteins in cells. It is clinically important to identify novel differentially expressed proteins (DEPs) from EVs in AML that could be used as biomarkers

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Cell, Stem Cell, Fibroblast

DISEASE(S): Acute Leukemia

SUBMITTER: Hyoseon Kim  

LAB HEAD: Kwang Pyo Kim

PROVIDER: PXD022758 | Pride | 2020-12-03

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
20170824_leukemia_F1-1.raw Raw
20170824_leukemia_F1-2.raw Raw
20170824_leukemia_F1-3.msf Msf
20170824_leukemia_F1-3.mzML Mzml
20170824_leukemia_F1-3.mzid.gz Mzid
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