Proteomics

Dataset Information

0

Identification of interacting proteins with circPLCE1-411 in hunan colorectal cancer cell by LC-MS


ABSTRACT: To identify the unknown interacting proteins with circPLCE1-411, we extracted the proteins from HCT8 cells and performed co-immunoprecipitation assays with Flag antibody. Then the proteins were subjected to mass spectrometry

INSTRUMENT(S): LTQ

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Colon

DISEASE(S): Colon Cancer

SUBMITTER: Zhenxing Liang  

LAB HEAD: Ping Lan

PROVIDER: PXD023617 | Pride | 2021-09-10

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
LZX_50kd.dat Other
LZX_50kd.mgf Mgf
LZX_50kd.raw Raw
LZX_Flag.dat Other
LZX_Flag.mgf Mgf
Items per page:
1 - 5 of 9
altmetric image

Publications

A novel NF-κB regulator encoded by circPLCE1 inhibits colorectal carcinoma progression by promoting RPS3 ubiquitin-dependent degradation.

Liang Zhen-Xing ZX   Liu Hua-Shan HS   Xiong Li L   Yang Xin X   Wang Feng-Wei FW   Zeng Zi-Wei ZW   He Xiao-Wen XW   Wu Xian-Rui XR   Lan Ping P  

Molecular cancer 20210819 1


<h4>Background</h4>Constitutive activation of nuclear factor-κB (NF-κB) signaling plays a key role in the development and progression of colorectal carcinoma (CRC). However, the underlying mechanisms of excessive activation of NF-κB signaling remain largely unknown.<h4>Methods</h4>We used high throughput RNA sequencing to identify differentially expressed circular RNAs (circRNAs) between normal human intestinal epithelial cell lines and CRC cell lines. The identification of protein encoded by ci  ...[more]

Similar Datasets

2022-02-15 | PXD019954 | Pride
2023-05-10 | PXD037028 | Pride
2023-05-10 | PXD037292 | Pride
2021-11-15 | PXD024693 | Pride
2023-11-02 | PXD037447 | Pride
2023-11-02 | PXD037024 | Pride
2023-05-18 | PXD041040 | Pride
2018-06-01 | GSE99425 | GEO
2022-02-04 | E-MTAB-11322 | biostudies-arrayexpress
2012-04-01 | E-GEOD-35161 | biostudies-arrayexpress