Proteomics

Dataset Information

0

Identification of interacting proteins with circINSIG1-121 in hunan colorectal cancer cell by LC-MS

ABSTRACT: To identify the unknown interacting proteins with circINSIG1-121, we extracted the proteins from HCT8 cells and performed co-immunoprecipitation assays with circINSIG1-121 antibody. Then the proteins were subjected to mass spectrometry

INSTRUMENT(S): LTQ

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Colon

SUBMITTER: Zhenxing Liang  

LAB HEAD: Li Xiong

PROVIDER: PXD037028 | Pride | 2023-05-10

REPOSITORIES: Pride

Json Xml
altmetric image

Publications

A novel protein encoded by circINSIG1 reprograms cholesterol metabolism by promoting the ubiquitin-dependent degradation of INSIG1 in colorectal cancer.

Xiong Li L   Liu Hua-Shan HS   Zhou Chi C   Yang Xin X   Huang Liang L   Jie Hai-Qing HQ   Zeng Zi-Wei ZW   Zheng Xiao-Bin XB   Li Wen-Xin WX   Liu Zhan-Zhen ZZ   Kang Liang L   Liang Zhen-Xing ZX  

Molecular cancer 20230422 1

<h4>Background</h4>Hypoxia is a hallmark of solid tumors and leads to the metabolic reprogramming of cancer cells. The role of epigenetic regulation between hypoxia and aberrant cholesterol metabolism in colorectal cancer (CRC) remains elusive.<h4>Methods</h4>Hypoxia-responsive circular RNAs (circRNAs) were identified by high throughput RNA sequencing between CRC cells cultured under normoxia or hypoxia. The protein-coding potential of circINSIG1 was identified by polysome profiling and LC-MS. T  ...[more]

Similar Datasets

Proteomics Identification of a novel protein circINSIG1-121 in hunan colorectal cancer cell by LC-MS
2023-05-10 | PXD037292 | Pride
Proteomics Receptor identification of Cyr61 on hunan colorectal cancer cell by LC-MS
2022-02-15 | PXD019954 | Pride
Proteomics Identification of interacting proteins with circPLCE1-411 in hunan colorectal cancer cell by LC-MS
2021-09-10 | PXD023617 | Pride
Proteomics Identification of circGlis3 binding proteins in MS-1 cells by LC-MS
2021-11-15 | PXD024693 | Pride
Proteomics Identification of circGlis3 binding proteins in MIN6 cells by LC-MS
2023-11-02 | PXD037024 | Pride
Proteomics Identification of a novel Glis3-348aa protein in MIN6 cells by LC-MS
2023-11-02 | PXD037447 | Pride
Proteomics A Treg specific long non-coding RNA maintains immune-metabolic homeostasis in ageing liver
2023-05-18 | PXD041040 | Pride
Genomics Vesicle treatment of HCT8 cells
2018-06-01 | GSE99425 | GEO
Transcriptomics YTHDF3 improves translation initiation of mRNAs with N6-methyladenosine methylation at 5’ untranslated region by facilitating eIF2AK2 recruitment in oxaliplatin-resistant colorectal cancer - RNA-seq cell line comparison
2022-02-04 | E-MTAB-11322 | biostudies-arrayexpress
Transcriptomics Sindbis virus induces the production of a novel class of endogenous siRNAs in Aedes aegypti mosquitoes
2012-04-01 | E-GEOD-35161 | biostudies-arrayexpress