Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Placenta
DISEASE(S): Zika Fever
SUBMITTER: Abiel Roche
LAB HEAD: Dr. Abiel Roche-Lima
PROVIDER: PXD023964 | Pride | 2022-06-09
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
Set_of_8_files.msf | Msf | |||
Set_of_8_files.mzML | Mzml | |||
Set_of_8_files_14dic2020.mzid.gz | Mzid | |||
TMT_Fraction_1_Gabriel_9May19.raw | Raw | |||
TMT_Fraction_2_Gabriel_9May19.raw | Raw |
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Journal of molecular histology 20210715 2
Zika virus (ZIKV) infection has been associated with fetal abnormalities by compromising placental integrity, but the mechanisms by which this occurs are unknown. Flavivirus can deregulate the host proteome, especially extracellular matrix (ECM) proteins. We hypothesize that a deregulation of specific ECM proteins by ZIKV, affects placental integrity. Using twelve different placental samples collected during the 2016 ZIKV Puerto Rico epidemic, we compared the proteome of five ZIKV infected sampl ...[more]