Proteomics

Dataset Information

0

Comparative analysis of therapeutic effects between medium cut-off and high flux dialyzers using metabolomics and proteomics


ABSTRACT: This study compared the therapeutic effects of medium cut-off (MCO) and high flux (HF) dialyzers using metabolomics and proteomics. This was a single-center prospective trial of 20 patients receiving maintenance hemodialysis (HD). A consecutive dialyzer membrane was used for 15-week study periods as follows: 1st HF dialyzer, MCO dialyzer, 2nd HF dialyzer, for 5 weeks respectively. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis was used to identify proteins.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Plasma

DISEASE(S): End Stage Renal Disease

SUBMITTER: Kyunggon Kim  

LAB HEAD: Kyunggon Kim

PROVIDER: PXD026907 | Pride | 2021-11-03

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
200613-BSUH_SWATH_S01.wiff Wiff
200613-BSUH_SWATH_S01.wiff.scan Wiff
200613-BSUH_SWATH_S02.wiff Wiff
200613-BSUH_SWATH_S02.wiff.scan Wiff
200613-BSUH_SWATH_S03.wiff Wiff
Items per page:
1 - 5 of 162
altmetric image

Publications

Comparative analysis of therapeutic effects between medium cut-off and high flux dialyzers using metabolomics and proteomics: exploratory, prospective study in hemodialysis.

Kim Hyo Jin HJ   Seong Eun Young EY   Lee Wonho W   Kim Suhkmann S   Ahn Hee-Sung HS   Yeom Jeonghun J   Kim Kyunggon K   Kwon Chae Hwa CH   Song Sang Heon SH  

Scientific reports 20210830 1


In this single-center prospective study of 20 patients receiving maintenance hemodialysis (HD), we compared the therapeutic effects of medium cut-off (MCO) and high flux (HF) dialyzers using metabolomics and proteomics. A consecutive dialyzer membrane was used for 15-week study periods: 1st HF dialyzer, MCO dialyzer, 2nd HF dialyzer, for 5 weeks respectively. <sup>1</sup>H-nuclear magnetic resonance was used to identify the metabolites and liquid chromatography-tandem mass spectrometry (LC-MS/MS  ...[more]

Similar Datasets

2023-10-24 | PXD040099 | Pride
2024-08-14 | PXD040122 | Pride
2023-10-18 | PXD042286 | Pride
2022-12-01 | PXD034996 | Pride
2022-02-15 | PXD028251 | Pride
2023-11-30 | PXD041005 | Pride
2024-10-17 | PXD024304 | Pride
2012-11-08 | E-GEOD-42044 | biostudies-arrayexpress
2012-11-08 | E-GEOD-42119 | biostudies-arrayexpress
2024-09-09 | E-MTAB-14321 | biostudies-arrayexpress