Dataset Information
Effect of control siRNA knockdown on EndoC-bH1 cell lysate proteome (pilot TMT experiment)
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Type B Pancreatic Cell, Endocrine Pancreas, Cell Culture
SUBMITTER: 
Maria Ryaboshapkina
LAB HEAD: Raphael Scharfmann
PROVIDER: PXD027898 | Pride | 2022-04-07
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| PE167_2019_GP_PCSK9_A.msf | Msf | |||
| PE167_2019_GP_PCSK9_A.msfView | Msf | |||
| PE167_2019_GP_PCSK9_A.pdResult | Other | |||
| PE167_2019_GP_PCSK9_A.pdResultView | Other | |||
| PE167_2019_GP_PCSK9_A.pdStudy | Other |
Items per page: 1 - 5 of 55 |
Publications
Characterization of the Secretome, Transcriptome, and Proteome of Human β Cell Line EndoC-βH1.
Molecular & cellular proteomics : MCP 20220402 5
Early diabetes research is hampered by limited availability, variable quality, and instability of human pancreatic islets in culture. Little is known about the human β cell secretome, and recent studies question translatability of rodent β cell secretory profiles. Here, we verify representativeness of EndoC-βH1, one of the most widely used human β cell lines, as a translational human β cell model based on omics and characterize the EndoC-βH1 secretome. We profiled EndoC-βH1 cells using RNA-seq, ...[more]
