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Huh7 cells proteoic analysis withtomatidine treatment at 6 and 16 hours post-treatment

ABSTRACT: Tomatidine, a natural steroidal alkaloid from unripe green tomatoes has been shown to exhibit many health benefits. We recently provided in vitro evidence that tomatidine reduces the infectivity of Dengue virus (DENV) and Chikungunya virus (CHIKV), two medically important arthropod-borne human infections for which no treatment options are available. The objective of this mass spectrometry analysis was to determine possible proteomic changes in the human cell line Huh7 induced by tomatidine which may be indicative of the underlying antiviral activity of tomatidine.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Hepatocyte, Cell Culture

DISEASE(S): Disease Free

SUBMITTER: Berit Troost-Kind

LAB HEAD: Jolanda M. Smit

PROVIDER: PXD028693 | Pride | 2021-11-18

REPOSITORIES: Pride

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			Action	DRS
	180829_B_Troost_MJ330_Exp156_Sample_1_2ul_out_of_50.raw	Raw
	180829_B_Troost_MJ330_Exp156_Sample_2.raw	Raw
	180829_B_Troost_MJ330_Exp156_Sample_5.raw	Raw
	180829_B_Troost_MJ330_Exp156_Sample_6.raw	Raw
	180829_B_Troost_MJ330_Exp157_Sample_10.raw	Raw

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