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Mutant p53 interactome study with IP-MS

ABSTRACT: Inactivating TP53 mutations lead to a loss of function of p53, but can also often result in oncogenic gain-of-function (GOF) of mutant p53 (mutp53) proteins which promote tumor development and progression. The GOF activities of TP53 mutations are well documented, but the mechanisms involved remain poorly understood. Here, we study the mutp53 interactome with IP-MS.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Zhen Chen

LAB HEAD: Junjie Chen

PROVIDER: PXD047094 | Pride | 2023-11-27

REPOSITORIES: Pride

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	MaxQuant_1.5.8.3.zip	Other
	Q_Zhen_WC_GE_p53_1_1.raw	Raw
	Q_Zhen_WC_GE_p53_1_2.raw	Raw
	Q_Zhen_WC_GE_p53_1_3.raw	Raw
	Q_Zhen_WC_GE_p53_2_1.raw	Raw

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