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Exploring the vault interactome in the divergent eukaryote Trypanosoma brucei

ABSTRACT: Many, but not all Eukaryotes have protein-enclosed compartments called vaults. Vaults are composed of multiple copies of the major vault protein (MVP), symmetrically assembled into a basket like shell. Whilst there is some evidence that these compartments are engaging in mRNA maturation and intriguing structural information of the vault shell is available, the function of vaults remains largely elusive. Here, we set out to explore the vault interactome in the early branching eukaryote Trypanosoma brucei employing a combination of affinity capture and TurboID proximity labelling.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Trypanosoma Brucei

TISSUE(S): Permanent Cell Line Cell

DISEASE(S): Trypanosomiasis

SUBMITTER: Martin Zoltner

LAB HEAD: Dr. Martin Zoltner

PROVIDER: PXD056004 | Pride | 2024-12-12

REPOSITORIES: Pride

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			Action	DRS
	BioID.combined.txt.rar	Txt
	BioID_Control_1.raw	Raw
	BioID_Control_2.raw	Raw
	BioID_Control_3.raw	Raw
	BioID_MVP1_1.raw	Raw

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