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Expression data from Ribonuclease Inhibitor (RI/Rnh1) deficient Human K562 cells

ABSTRACT: Expression data from Ribonuclease Inhibitor (RI/Rnh1) deficient Human K562 cells

PROVIDER: PRJEB19635 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	ERR1855450_1.fastq.gz	Fastqsanger.gz
	ERR1855450_2.fastq.gz	Fastqsanger.gz
	ERR1855445_1.fastq.gz	Fastqsanger.gz
	ERR1855445_2.fastq.gz	Fastqsanger.gz
	ERR1855446_1.fastq.gz	Fastqsanger.gz

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Expression data from Ribonuclease Inhibitor (RI/Rnh1) deficient Human K562 cells

Project description:Summary: Ribonuclease Inhibitor (RI also known as Rnh1) is a 50 kDa, ubiquitously expressed leucine-rich repeat (LRR) protein. It is localized in cytosol and binds to pancreatic-type ribonucleases and inhibit their function. However, the entire biological role for Rnh1 is unknown. We generated RNH1 knock out K562 cells by CRISPR/Cas9 method. Here we studied differential gene expression from wild type and RNH1 knock out K562 cells by RNA-Seq analysis. Overall design: Total RNA was isolated from wild type and RNH1 deficient K562 cells.

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