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CoMtb alters the immune landscape following Mtb infection [C3H scRNAseq]

ABSTRACT: CoMtb alters the immune landscape following Mtb infection [C3H scRNAseq]

PROVIDER: PRJNA1104528 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR28803737_1.fastq.gz	Fastqsanger.gz
	SRR28803737_2.fastq.gz	Fastqsanger.gz
	SRR28803738_1.fastq.gz	Fastqsanger.gz
	SRR28803738_2.fastq.gz	Fastqsanger.gz
	SRR28803739_1.fastq.gz	Fastqsanger.gz

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CoMtb alters the immune landscape following Mtb infection [C3H scRNAseq]

Project description:To gain further insights into lesion development and effects of CoMtb on immune responses during infection. we performed single-cell RNA sequencing (scRNAseq) and flow cytometry analysis of lungs from Mtb-infected animals with and without CoMtb immediately pre-infection and at 10. 17 and 34 days after CD infection. We found that CoMtb induces rapid recruitment and activation of T cells. macrophage activation. and diminished late neutrophil responses.

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