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RNA Sequencing of C elegans control and mutant worms after 24 hour P.aeruginosa infection

ABSTRACT: RNA Sequencing of C elegans control and mutant worms after 24 hour P.aeruginosa infection

PROVIDER: PRJNA564575 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR10087139.fastq.gz	Fastqsanger.gz
	SRR10087140.fastq.gz	Fastqsanger.gz
	SRR10087141.fastq.gz	Fastqsanger.gz
	SRR10087142_1.fastq.gz	Fastqsanger.gz
	SRR10087142_2.fastq.gz	Fastqsanger.gz

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RNA Sequencing of C elegans control and mutant worms after 24 hour P.aeruginosa infection

Project description:Purpose: After infection there was significant decrease in the lifespan of mutant animals . To decipher the mechanism responsible and the changes in the gene expression of mutant worms Methods: Control and mutant worms were exposed at young adult stage to P.aeruginosa PA14 infection for 24 hours. Total RNA was extracted and RNA sequencing was done following standard protocols Results: Detailed analysis of the transcriptomic data show that immune genes were significantly upregulated which have role in lifespan Conclusions: This study showed the role of pathogenic infection in the life span modulation

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