Sort   by:  
 Page size 
0
ProteomicsAlterations in lipid profile of the aging kidney identified by MALDI imaging mass spectrometry
...ipids in various metabolic processes during kidney aging, we conducted MALDI imaging mass spectrometry (MALDI-IMS) analysis in kidneys harvested from young (2 months old, n=3) and old mice (24 months old, n=3). MALDI-IMS analysis showed an increase in ceramide level and a decrease in sphingomyelin (SM) a...
ORGANISM(S): Mus Musculus (mouse) 
2019-06-10 | PXD013860 | Pride
Renal fibrosis Lipidomics Chronic kidney disease Ckd Ims 
0
ProteomicsMouse muscle proteome for sarcopenia study
...Aging and lack of exercise are ones of most important attributing causes of muscle loss. To find a novel factor contributing to muscle loss, we performed mass spectrometry-based proteomic analysis in gastrocnemii of unloading and old mice compared to those of exercised and young mice.
ORGANISM(S): Mus Musculus (mouse) 
2024-08-10 | PXD043715 | Pride
Lc-ms Sarcopenia Mouse Lfq Muscle 
0
ProteomicsRat liver ESI-MS/MS - Proteomic analysis of one-carbon metabolism-related marker in liver of rat offspring
one-carbon metabolism in the liver plays a critical role in placental and fetal growth. Impaired functioning of one-carbon metabolism is associated with increased homocysteine (Hcy) levels. In this study, we applied a comprehensive proteomic approach to identify differential expression of proteins r...
ORGANISM(S): Rattus Norvegicus (rat) 
2015-09-07 | PXD002578 | Pride
Rat Liver Esi-ms/ms 
0
ProteomicsInhibition of Alternative Complement Pathway May Cause Secretion of Factor B, Enabling an Early Detection of Pancreatic Cancer
This study aims to elucidate the cellular mechanisms underlying the secretion of factor B (CFB), recognized for its dual role as an early biomarker of pancreatic ductal adenocarcinoma (PDAC) and as the initiating substrate for the alternative complement pathway (ACP), a crucial component of the inna...
ORGANISM(S): Homo Sapiens (human) 
2024-05-21 | PXD047043 | Pride
Cancer biomarker Complement factor h Pancreatic ductal adenocarcinoma Proteomics Complement factor b Adrenomedullin Alternative pathway 
0
ProteomicsLPS-stimulated endothelial cells using SILAC
Severe sepsis and septic shock, which occur with high incidence and are prevalent in the emergency department setting, are among the most common causes of death in hospitalized patients worldwide, and there has been a continuous increase in the incidence of sepsis of approximately 5–10% per year. En...
ORGANISM(S): Homo Sapiens (human) 
2015-10-05 | PXD002220 | Pride
Biomarker Moesin Sepsis Secretome Silac 
0
Proteomicsmouse liver microsomes phosphorylation
The microsomes are re-formed vesicle-like artifacts, not ordinarily present in living cells, from pieces of the endoplasmic reticulum (ER), plasma membrane, mitochondria, and Golgi apparatus of broken eukaryotic cells. Typically, microsomes are separated by differential centrifuged from homogenized ...
ORGANISM(S): Mus Musculus (mouse) 
2015-08-24 | PXD002221 | Pride
Phosphorylation Mouse Liver Microsome 
0
ProteomicsHuman Placenta profilling LTQ-OrbiTrap
Profilling normal human placantal proteomes using LTQ-OrbiTrap
ORGANISM(S): Homo Sapiens (human) 
2015-05-26 | PXD000754 | Pride
Human Placenta C-hpp Normal 
0
ProteomicsSilica-cSilica-coated-magnetic-nanoparticle-induced cytotoxicity is reduced in microglia by glutathione and citrate discovered using integrated omics analysisoated-magnetic-nanoparticle-induced cytotoxicity is reduced in microglia by glutathione and citrate discovered using integrated omics analysis
Exposure to nanoparticles leads to their accumulation in the brain, but drug development to counteract this nanotoxicity remains challenging. Here we assessed the effect of silica-coated-magnetic nanoparticles containing the rhodamine B isothiocyanate dye [MNPs@SiO2(RITC)] on microglia through integ...
ORGANISM(S): Mus Musculus (mouse) 
2022-02-15 | PXD020225 | Pride
nanotoxicity Machine learning integrated omics Silica-coated- magnetic nanoparticles Microglia Silica-coated- magnetic nanoparticles  nanotoxicity  integrated omics 
0
ProteomicsZebrafish embryo_phosphorylation_18O labeling
The zebrafish (Danio rerio) is a popular animal model in studies of vertebrate development and organogenesis. Recent research has shown a similarity of approximately 70% between the human and zebrafish genomes and of 84% in human disease-causing genes, specifically. Zebrafish embryos have a number o...
ORGANISM(S): Danio Rerio (zebrafish) (brachydanio Rerio) 
2015-10-14 | PXD002232 | Pride
18o labeling : zebrafish embryo Global phosphoproteome 
0
ProteomicsBALF proteomics - In-depth proteomic analysis of human bronchoalveolar lavage fluid towards the biomarker discovery for lung cancers
Lung cancer is one of the most common cancers and the leading cause of cancer-related mortality. Because the early diagnosis of the cancer is one of the major goals in lung cancer research, the molecule-based sensitive detection of biomarkers from bronchoalveolar lavage fluid (BALF) to diagnose the ...
ORGANISM(S): Homo Sapiens (human) 
2019-05-30 | PXD012645 | Pride
Depletion Lung cancer Balf 
Sort   by:  
 Page size