Project description:Comparison of expression of known 'iron' genes in liver, spleen and duodenum of C57BL/6J and SWR mouse strains which have low and high basal iron levels respectively.
Project description:A variety of human cell lines, were grown, RNA was extracted, and gene expression quantified using Affymetrix hgu133plus2 arrays. Expression of genes was compared to the rate of metabolism of the bioreductive prodrug PR-104A, and genes with expression shown to be statistically significantly correlated to pro-drug metabolic rate were chosen for further investigation.
Project description:Evaluation and comparison of biological responses of rats and gene expression responses of the kidney in rats exposed to different doses of Puromycin [CAS:53-79-2;CHEBI:17939]
Project description:A common reference experiment design was performed. mRNAs from 149 New Zealand colorectal cancer samples were labeled with Cy5 and a common reference RNA from 12 cell lines were labeled with Cy3. Data were log2 transformed and normalized. Class prediction was performed to identify genes capable of predicting future samples.
Project description:Lymph node sections from 29 patients with StageIIIB and IIIC melanoma, with divergent clinical outcome including 16 poor and 13 good prognosis patients as defined by time to tumor progression (TTP), were profiled using MWG oligonucleotide arrays,.