Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Chromatin immunoprecipitation using promoter microarrays to identify genes occupied by the transcriptional regulators HNF1a, HNF4a and HNF6, together with RNA polymerase II, in human liver and pancreatic islets


ABSTRACT: Here, we use chromatin immunoprecipitation combined with promoter microarrays to identify the genes occupied by the transcriptional regulators HNF1a, HNF4a and HNF6, together with RNA polymerase II, in human liver and pancreatic islets.

ORGANISM(S): Homo sapiens

SUBMITTER: Robert Latek 

PROVIDER: E-MEXP-68 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

altmetric image

Publications


The transcriptional regulatory networks that specify and maintain human tissue diversity are largely uncharted. To gain insight into this circuitry, we used chromatin immunoprecipitation combined with promoter microarrays to identify systematically the genes occupied by the transcriptional regulators HNF1alpha, HNF4alpha, and HNF6, together with RNA polymerase II, in human liver and pancreatic islets. We identified tissue-specific regulatory circuits formed by HNF1alpha, HNF4alpha, and HNF6 with  ...[more]

Similar Datasets

2005-06-03 | E-WMIT-4 | biostudies-arrayexpress
2006-05-09 | E-WMIT-6 | biostudies-arrayexpress
2006-05-09 | E-WMIT-11 | biostudies-arrayexpress
2006-05-09 | E-WMIT-8 | biostudies-arrayexpress
2007-07-05 | E-TABM-272 | biostudies-arrayexpress
2006-05-09 | E-WMIT-12 | biostudies-arrayexpress
2008-06-11 | E-TABM-474 | biostudies-arrayexpress
2008-02-28 | E-TABM-409 | biostudies-arrayexpress
2008-11-04 | E-TABM-410 | biostudies-arrayexpress
2008-06-11 | E-TABM-485 | biostudies-arrayexpress