Browse
Submit Data
Databases
API
Help

Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcription profiling of Arabidopsis lrx1 root hair mutant and the suppressor mutations lrx1 rol1-1 and lrx1 rol1-2

ABSTRACT: Genome wide gene expression profile of the lrx1 root hair mutant and the suppressor mutations lrx1 rol1-1 and lrx1 rol1-2.

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Markus Pauly

PROVIDER: E-MEXP-722 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Publications

The Arabidopsis root hair cell wall formation mutant lrx1 is suppressed by mutations in the RHM1 gene encoding a UDP-L-rhamnose synthase.

Diet Anouck A Link Bruce B Seifert Georg J GJ Schellenberg Barbara B Wagner Ulrich U Pauly Markus M Reiter Wolf-Dieter WD Ringli Christoph C

The Plant cell 20060609 7

Cell and cell wall growth are mutually dependent processes that must be tightly coordinated and controlled. LRR-extensin1 (LRX1) of Arabidopsis thaliana is a potential regulator of cell wall development, consisting of an N-terminal leucine-rich repeat domain and a C-terminal extensin-like domain typical for structural cell wall proteins. LRX1 is expressed in root hairs, and lrx1 mutant plants develop distorted root hairs that often swell, branch, or collapse. The aberrant cell wall structures fo ...[more]

PMID: 16766693

Similar Datasets

Transcription profiling of human lobular and ductal invasive carcinomas vs normal breast tissue from the same patient to identify gene expression profiles of ductal and lobular carcinomas in relation to normal ductal and lobular cells

Project description:The aim of our study was to identify gene expression profiles of ductal and lobular carcinomas in relation to normal ductal and lobular cells. We examined ten mastectomy specimens from postmenopausal breast cancer patients. Ductal and lobular tumor and normal cells were microdissected from cryosections. Fifty nanograms of total RNA were amplified and labeled by PCR and in vitro transcription. GCOS pairwise comparison algorithm and rank products have identified multiple genes that are differentially expressed in comparisons between ductal and lobular tumor and normal cell types. The results suggest that these genes are involved in epithelial-mesenchymal transition, TGFbeta and Wnt signaling. These changes are present in both tumor types but appear to be more prominent in lobular carcinomas. Ten surgical specimens obtained by mastectomy from postmenopausal patients with invasive ductal (IDC) and lobular breast (ILC) carcinomas were investigated. Of these, 5 were IDCs and 5 were ILCs. Tumor and normal tissues from the same mammary gland were identified by an experienced pathologist, snap-frozen in liquid nitrogen and stored at -80ÂºC for further analysis. Microdissection, RNA isolation, amplification, labeling and microarray analysis are described in sample definitions. Samples from particular cell types (normal ductal, normal lobular, tumor ductal, tumor lobular - 10, 10, 5, 5 samples, respectively) were considered as biological replicates and were compared in between.

2007-11-01 | E-GEOD-5764 | biostudies-arrayexpress

Transcription profiling of Zea mays leaves from variety MON810 (Helen Bt) grown in agricultural fields at 2 levels of nitrogen fertilization

Project description:Comparison of the transcriptome profiles of a widely commercialized MON810 maize variety (HelenBt) at two levels of nitrogen fertilization. Variety Helen Bt; obtained by Advanta; authorized the 11/08/2005; now commercialized by Limagrain Iberica. Conventional nitrogen fertilization compared to not nitrogen fertilization during the season.

2010-09-21 | E-MEXP-2368 | biostudies-arrayexpress

Transcription profiling of Zea mays leaves from variety Helen grown in agricultural fields at 2 levels of nitrogen fertilization

Project description:Comparison of the transcriptome profiles of a widely commercialized maize variety (Helen) at two levels of nitrogen fertilization. Conventional nitrogen fertilization compared to not nitrogen fertilization during the season.

2010-09-21 | E-MEXP-2367 | biostudies-arrayexpress

Transcription profiling of Zea mays leaves from MON810 (Helen Bt) and its near-isogenic couterpart (Helen) grown in agricultural fields

Project description:Comparison of the transcriptome profiles of a widely commercialized maize MON810 variety and its non-GM near-isogenic counterpart grown in agricultural fields. The Helen variety was commercialized by Limagrain Iberica. Variety Helen B was obtained by Advanta; authorized the 11/08/2005; now commercialized by Limagrain Iberica. The insert integrated into the maize genome contains: Cauliflower Mosaic Virus 35S promoter + maize HSP70 intron (partial) + synthetic sequence coding for the Bacillus thuringensis CRYIA(b) insecticidal protein (truncated).

2010-09-21 | E-MEXP-2366 | biostudies-arrayexpress

Arabidopsis thaliana embryo sac transcriptome

Project description:differential expression between wild-type pistils of Arabidopsis thaliana at late 11 to late 12 floral stages, and similar stage pistils of coatlique mutant which lacks a functional embryo sac

2007-10-02 | E-MEXP-1246 | biostudies-arrayexpress

RNAi knock down of PAX3 in human eRMS and aRMS cell lines identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR

Project description:eRMS and aRMS cell lines were treated with small interference RNA (siRNA) specific for PAX3 or - as negative control - scrambled siRNA(Qiagen, Hombrechtikon, Switzerland). After 24hrs, 48hrs and 72hrs total RNA from each sample was used to prepare biotinylated target RNA using the Affymetrix 'Small Sample Labelling Protocol vII' . Subsequently, microarray analysis was performed.

2007-06-08 | E-MEXP-1124 | biostudies-arrayexpress

Transcription profiling by array of human peripheral blood lymphocytes or haemopoietic stem cells at the time of transduction with a gammaretroviral vector

Project description:Expression profile comparison of peripheral blood lymphocytes (PBL) or haemopoietic stem cells (HSC) at the time of transduction with a gammaretroviral vector. The analysis is performed in the context of two different gene therapy clinical trials (Recchia et al, 2006; Aiuti et al, 2007) based on autologous infusion of human T cells or CD34+ haemopoietic progenitor cells gene-corrected with an moloney leukemia virus-derived vector (MLV-vector). T cells and CD34+ cells were isolated from patients and pre-stimulated in vitro with cytokines prior to transduction with the vector and re-infusion in patient. The expression profiles of T cells and CD34+ cells were analysed by microarray just after cytokine stimulation, providing information on the transcriptional activity of these two target cells at the time of transduction.

2010-12-30 | E-MEXP-2983 | biostudies-arrayexpress

Transcription profiling of Zea mays leafs of MON810 (Helen Bt) and near-isogenic commercial varieties (Helen) gorwn in low nitrogen conditions

Project description:Comparison of the transcriptome profiles of a widely commercialized maize MON810 variety and its non-GM near-isogenic counterpart subjected to low N fertilization farming practices

2010-09-21 | E-MEXP-2364 | biostudies-arrayexpress

Transcription profiling of mouse Notch1 deficient in hair follicles

Project description:Notch1 deficient hair matrix keratinocytes have lower mitotic rates, resulting in smaller follicles with fewer cells. In addition, the ratio of melanocytes to keratinocytes is greatly reduced. Microarray was performed to study downstream mechanism of Notch1-deficiency Experiment Overall Design: Microarray was first performed using HF_emN1-1 and HF_anN1-1 samples. Later, HF_emN1-2, HF_anN1-2, HF_WT-1, and HF_WT-2 were used to perform another set of microarray. anN1s and WTs were used as wild-type controls.

2008-06-15 | E-GEOD-6867 | biostudies-arrayexpress

Transcription profiling of Gata3 conditional knock out mice to investigate epidermis and hair follicle differentiation

Project description:Transcriptome analysis on Gata3 conditional knock out murine hair follicles. Background. The transcription factor Gata3 is critically involved in epidermis and hair follicle differentiation. Yet, little is known about how Gata3 co-ordinates stem cell lineage determination in skin, which processes are mostly implicated and how Gata3 differentially regulates distinct cell populations within the hair follicle. Here, we describe a conditional Gata3-/- mouse (K14-Gata3-/-) in which Gata3 is specifically deleted in epidermis and hair follicles. Principal findings. K14-Gata3-/- mice show aberrant postnatal growth and development, delayed hair growth and maintenance, abnormal hair follicle organization and irregular pigmentation. After the first hair cycle, the germinative layer surrounding the dermal papilla was not restored; instead, proliferation was pronounced in basal epidermal cells. Transcriptome analysis of laser-dissected K14-Gata3-/- hair follicles as compared to wild type littermate controls, revealed mitosis, epithelial differentiation and the Notch, WNT and BMP signalling pathways to comprise significantly overrepresented processes. Conclusions. Subsequent elucidation of these pathways at the RNA and protein levels and physiologic endpoints shows that Gata3 integrates diverse signalling networks to regulate the balance between hair follicle and epidermal cell fates.

2007-01-01 | E-MEXP-634 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data