Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Dm Snail Affymetrix ChIP

ABSTRACT: Genomewide mapping of D. melanogaster Snail protein binding during embryonic development at 2-4 hrs after egg-laying. Two independent repeats were assayed and preimmune-serum was used as a control. The enriched DNA was hybridized to high density Affymetrix GeneChip Drosophila Tiling 1.0R array

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Charles Girardot

PROVIDER: E-MTAB-1589 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Publications

A conserved role for Snail as a potentiator of active transcription.

Rembold Martina M Ciglar Lucia L Yáñez-Cuna J Omar JO Zinzen Robert P RP Girardot Charles C Jain Ankit A Welte Michael A MA Stark Alexander A Leptin Maria M Furlong Eileen E M EE

Genes & development 20140108 2

The transcription factors of the Snail family are key regulators of epithelial-mesenchymal transitions, cell morphogenesis, and tumor metastasis. Since its discovery in Drosophila ∼25 years ago, Snail has been extensively studied for its role as a transcriptional repressor. Here we demonstrate that Drosophila Snail can positively modulate transcriptional activation. By combining information on in vivo occupancy with expression profiling of hand-selected, staged snail mutant embryos, we identifie ...[more]

PMID: 24402316

Similar Datasets

Dm Lmd 6-8hrs Affymetrix ChIP

Project description:Genomewide mapping of D. melanogaster Lame duck protein binding at 6-8hrs after egg laying. Two different rabbit antibodies were used to precipitate the Lmd protein isoform in biological replicates. Additionally a rabbit preimmune-serum was used as a control. The enriched DNA was hybridized to high density Affymetrix GeneChip Drosophila Tiling 1.0R array.

2014-03-01 | E-MTAB-1283 | biostudies-arrayexpress

Dm Ttk69 6-8hrs Affymetrix ChIP

Project description:Genomewide mapping of D. melanogaster Tramtrack69 protein binding at 6-8hrs after egg laying. Two different rabbit antibodies were used to precipitate the Tramtrack69 protein isoform in 3 biological replicates. Additionally a rabbit preimmune-serum was used as a control for every precipitation. The enriched DNA was hybridized to high density Affymetrix GeneChip Drosophila Tiling 1.0R array.

2014-03-01 | E-MTAB-1287 | biostudies-arrayexpress

Chromatin immunoprecipitation of Drosophila to identify Bagpipe protein binding during embryonic development

Project description:Genomewide mapping of D. melanogaster Bagpipe protein binding during embryonic development. A unique timepoint (6-8 hrs after egg-laying) was assayed in two independent repeats. Two different antibodies were used to precipitate the Bagpipe protein. Additionally the respective preimmune-serum was used as a control for every precipitation. The enriched DNA was hybridized to high density Affymetrix GeneChip Drosophila Tiling 1.0R array.

2009-11-09 | E-TABM-648 | biostudies-arrayexpress

Chromatin immunoprecipitation of Drosophila to identify muscle differentiation factor Mef2 protein binding during embryonic development

Project description:Genomewide mapping of D. melanogaster the muscle differentiation factor Mef2 protein binding during embryonic development. Five consecutive timepoints (2-4, 4-6, 6-8, 8-10, 10-12 hrs after egg-laying) were assayed in two independent repeats each. Two different antibodies were used to precipitate the Mef2 protein. Additionally the respective preimmune-serum was used as a control for every precipitation. The enriched DNA was hybridized to high density Affymetrix GeneChip Drosophila Tiling 1.0R array.

2009-11-09 | E-TABM-649 | biostudies-arrayexpress

Chromatin immunoprecipitation of Drosophila to identify Twist protein binding during embryonic development

Project description:Genomewide mapping of D. melanogaster Twist protein binding during embryonic development. Three consecutive timepoints (2-4, 4-6, 6-8 hrs after egg-laying) were assayed in two independent repeats each. Two different antibodies were used to precipitate the Twist protein. Additionally the respective preimmune-serum was used as a control for every precipitation. The enriched DNA was hybridized to high density Affymetrix GeneChip Drosophila Tiling 1.0R array.

2009-11-09 | E-TABM-651 | biostudies-arrayexpress

Chromatin immunoprecipitation of Twist protein during embryonic development in Drosophila

Project description:Genomewide mapping of Drosophila Twist protein binding during embryonic development. Two consecutive timepoints (2-4 and 4-6 hrs after egg-laying) were assayed in four independent repeats each. Two different antibodies were used to precipitate the Twist protein. Additionally, preimmune-serum was used as a control. The enriched DNA was hybridized to custom designed tiling arrays optimized for assaying all E-box motifs outside repetitive or coding regions of the Drosophila melanogaster genome (average gap size = 290 bps).

2007-03-28 | E-TABM-159 | biostudies-arrayexpress

Chromatin immunoprecipitation of Mef2 protein in Drosophila during embryonic development

Project description:Genomewide mapping of Drosophila Mef2 protein binding during embryonic development. Five consecutive timepoints (2-4, 4-6, 6-8, 8-10, 10-12 hrs after egg-laying) were assayed in four independent repeats each. Two different antibodies were used to precipitate the Mef2 protein. Additionally the respective preimmune-serum was used as a control for every precipitation. The enriched DNA was hybridized to tiling arrays covering ~ 50% of the Drosophila melanogaster genome.

2006-06-06 | E-TABM-56 | biostudies-arrayexpress

Chromatin immunoprecipitation of Bagpipe protein in Drosophila during embryonic development

Project description:Genomewide mapping of D. melanogaster Bagpipe protein binding during embryonic development. One time point (6-8 hrs after egg-laying) were assayed in four independent repeats. Two different antibodies were used to precipitate the Bagpipe protein. Additionally the respective preimmune-serum was used as a control for every precipitation. The enriched DNA was hybridized to tiling arrays covering ~ 50% of the Drosophila melanogaster genome.

2007-10-11 | E-TABM-247 | biostudies-arrayexpress

Chromatin immunoprecipitation to identify Tinman protein binding during embryonic delelopment in D. melanogaster

Project description:Genomewide mapping of Drosophila Tinman protein binding during embryonic development. Three consecutive timepoints (2-4, 4-6, 6-8 hrs after egg-laying) were assayed in four independent repeats each. Two different antibodies were used to precipitate the Tinman protein. Additionally the respective preimmune-serum was used as a control for every precipitation. The enriched DNA was hybridized to tiling arrays covering ~ 50% of the Drosophila melanogaster genome.

2009-04-16 | E-TABM-558 | biostudies-arrayexpress

Genome-wide binding of Sd and Yki in imaginal discs

Project description:The transcription cofactor Yki drives growth and proliferation in part by controlling mitochondrial network formation. To determine if Yki and Sd are directly bound to DNA corresponding to mitochondrial genes, we used chromatin immunoprecipitation and whole genome tiling arrays (ChIP-chip) to identify regions bound by these factors in eye-antenna and wing imaginal discs. The supplementary .bed files contain all Yki or Sd binding sites (called at 5% FDR) in wing or eye-antenna imaginal discs, as well as shared Sd+Yki sites and associated target genes. Wing or eye-antenna imaginal discs ChIPped for Yki or Sd-GFP vs. input DNA from corresponding imaginal discs.

2012-10-03 | E-GEOD-26678 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data