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Genome-wide DNA methylation analysis of promoters in normal and immortalised and transformed human cell lines

ABSTRACT: Analysis of DNA methylation changes at promoters in the fetal human lung fibroblast cell line MRC5 over time (two time points: 50 and 100 population doublings) during immortalisation with the catalytic component of telomerase (hTERT) and in vitro transformation with SV40 Large T antigen and oncogenic H-RAS

ORGANISM(S): Homo sapiens

SUBMITTER: Jose de las Heras

PROVIDER: E-MTAB-2005 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Genome-wide expression analysis in normal and immortalised and transformed human cell lines

Project description:Analysis of expression changes in the fetal human lung fibroblast cell line MRC5 over time (two time points: 50 and 100 population doublings) during immortalisation with the catalytic component of telomerase (hTERT) and in vitro transformation with SV40 Large T antigen and oncogenic H-RAS

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