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Protein surface recognition using geometrically pure Ru(II) tris(bipyridine) derivatives.

ABSTRACT: This manuscript illustrates that the geometric arrangement of protein-binding groups around a ruthenium(II) core leads to dramatic differences in cytochrome c (cyt c) binding highlighting that it is possible to define synthetic receptors with shape complementarity to protein surfaces.

SUBMITTER: Filby MH

PROVIDER: S-EPMC3172587 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature

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Protein surface recognition using geometrically pure Ru(II) tris(bipyridine) derivatives.

Filby Maria H MH Muldoon James J Dabb Serin S Fletcher Nicholas C NC Ashcroft Alison E AE Wilson Andrew J AJ

Chemical communications (Cambridge, England) 20101123 1

This manuscript illustrates that the geometric arrangement of protein-binding groups around a ruthenium(II) core leads to dramatic differences in cytochrome c (cyt c) binding highlighting that it is possible to define synthetic receptors with shape complementarity to protein surfaces. ...[more]

PMID: 21103575

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