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Pd-catalyzed aldehyde to ester conversion: a hydrogen transfer approach.

ABSTRACT: Aliphatic and aromatic aldehydes are successfully converted into their corresponding esters using Pd(OAc)(2) and XPhos. This approach utilizes a hydrogen transfer protocol: concomitant reduction of acetone to isopropanol provides an inexpensive and sustainable approach that mitigates the need for other oxidants.

SUBMITTER: Tschaen BA

PROVIDER: S-EPMC3568929 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature

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Pd-catalyzed aldehyde to ester conversion: a hydrogen transfer approach.

Tschaen Brittany A BA Schmink Jason R JR Molander Gary A GA

Organic letters 20130115 3

Aliphatic and aromatic aldehydes are successfully converted into their corresponding esters using Pd(OAc)(2) and XPhos. This approach utilizes a hydrogen transfer protocol: concomitant reduction of acetone to isopropanol provides an inexpensive and sustainable approach that mitigates the need for other oxidants. ...[more]

PMID: 23320580

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