Ontology highlight
ABSTRACT:
SUBMITTER: Sander V
PROVIDER: S-EPMC6155399 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Sander Veronika V Patke Shantanu S Lee Jung Y JY Chang Young-Tae YT Davidson Alan J AJ
Molecules (Basel, Switzerland) 20170313 3
We describe the use of the fluorescent reporter compound CDr10b to label mid-intestinal structures in zebrafish larvae after simple immersion. CDr10b is deposited into the gut where it initially fills the lumen and is excreted. Using laser-mediated injury of the intestine, we show that CDr10b provides a useful readout of the integrity and repair of the epithelial cell barrier. In addition, CDr10b specifically labels the absorptive mid-intestine segment that is analogous to the mammalian small in ...[more]