Dataset Information
Convenient and Efficient Synthesis of Functionalized 2-Sulfenylindoles.
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ABSTRACT:
SUBMITTER: Doroszuk J
PROVIDER: S-EPMC7601631 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Publications
Convenient and Efficient Synthesis of Functionalized 2-Sulfenylindoles.
Materials (Basel, Switzerland) 20201010 20
A simple, efficient, and practical sulfenylation at the C2 position of <i>N</i>-tosylindoles under mild conditions was developed. The designed transformation is based on the reaction of <i>N</i>-tosylindoles with BuLi and <i>S</i>-alkyl, and <i>S</i>-aryl phosphorodithioates or thiotosylates to produce 2-sulfenylindoles in moderate to high yields. The presence of additional hydroxy, carboxy, or amino functionalities did not disturb the formation of products. ...[more]