Transcriptomics

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Loss of BTG1 function promotes ETV6-RUNX1-mediated leukemic transformation by upregulation of BCL6


ABSTRACT: Analysis of gene signatures in WT+Ctrl vs WT+ETV6-RUNX1, Btg1-/- and Btg1-/-+ETV6-RUNX1 in cKit+Ter119- fetal liver-derived hematopoietic progenitor cells (FL-HPCs). The Btg1-/-+ETV6-RUNX1 FL-HPCs display a strong increase in proliferation compared to WT+ETV6-RUNX1.

ORGANISM(S): Mus musculus

PROVIDER: GSE60589 | GEO | 2014/08/22

SECONDARY ACCESSION(S): PRJNA258597

REPOSITORIES: GEO

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