Genomics

Dataset Information

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SNP genotyping data from human iPSCs and human fibroblast cells


ABSTRACT: Human induced pluripotent stem cells changed the face of stem cell biology as they represent a renewable source of stem cells with the potential to differentiated into multiple lineages in a manner akin to embryonic stem cells that can be collected without the need for the destruction of an embryo. The potential of these cells as research tools is vast as they can be pushed to generate different cell types depending on research interest. Many complex diseasese.g. late onset alzheimer's disease and type 2 diabetes have known genetic risk factors that increase the likelihood of developing a disease. We performed whole genome SNP analysis to examine risk loci for different complex diseases in our donor iPS cells toanalyse disease risk and also assess which donor represents the best healthy background.

ORGANISM(S): Homo sapiens

PROVIDER: GSE61769 | GEO | 2014/09/26

SECONDARY ACCESSION(S): PRJNA262087

REPOSITORIES: GEO

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