Dataset Information
Pax3 interactome in mouse ES cell-derived mesodermal precursors
Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: GSE126362
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Trunk Somite, Mesoderm, Myotome, Dermomyotome, Embryonic Stem Cell, Paraxial Mesoderm
SUBMITTER: 
Alessandro Magli
LAB HEAD: Rita CR Perlingeiro
PROVIDER: PXD012693 | Pride | 2019-04-18
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| 44843.raw | Raw | |||
| 44843_ctrl_IP_peptide_amagli_1549926359.csv | Csv | |||
| 44843_ctrl_IP_protein_amagli_1549926362.csv | Csv | |||
| 44844.raw | Raw | |||
| 44844_Pax3_IP_peptide_amagli_1549916502.csv | Csv |
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Publications
Pax3 cooperates with Ldb1 to direct local chromosome architecture during myogenic lineage specification.
Nature communications 20190524 1
Chromatin looping allows enhancer-bound regulatory factors to influence transcription. Large domains, referred to as topologically associated domains, participate in genome organization. However, the mechanisms underlining interactions within these domains, which control gene expression, are not fully understood. Here we report that activation of embryonic myogenesis is associated with establishment of long-range chromatin interactions centered on Pax3-bound loci. Using mass spectrometry and gen ...[more]
