Ontology highlight
ABSTRACT:
INSTRUMENT(S): ultraflex
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Testis
SUBMITTER: Xinli Zhou
LAB HEAD: Hui Zhu
PROVIDER: PXD028014 | Pride | 2022-05-20
REPOSITORIES: Pride
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Frontiers in cell and developmental biology 20220425
Serine proteases are involved in many physiological activities as initiators of proteolytic cascades, and some members have been reported to play roles in male reproduction. Transmembrane serine protease 12 (TMPRSS12) has been shown to regulate sperm motility and uterotubal junction migration in mice, but its role in the testis remains unknown. In this study, we verified that TMPRSS12 was expressed in the spermatocytes and spermatids of testis and the acrosome of sperm. Mice deficient in <i>Tmpr ...[more]