Dataset Information
Comparative genomic hybridization of genomic DNA from two B. bronchiseptica strains and one B. pertussis strain and sequenced reference genomes by comparative genome hybridization (CGH)
Ontology highlight
ABSTRACT:
ORGANISM(S): Bordetella bronchiseptica
SUBMITTER: David Relman
PROVIDER: E-MEXP-399 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Species- and strain-specific control of a complex, flexible regulon by Bordetella BvgAS.
Journal of bacteriology 20060301 5
The Bordetella master virulence regulatory system, BvgAS, controls a spectrum of gene expression states, including the virulent Bvg(+) phase, the avirulent Bvg(-) phase, and at least one Bvg-intermediate (Bvg(i)) phase. We set out to define the species- and strain-specific features of this regulon based on global gene expression profiling. Rather than functioning as a switch, Bvg controls a remarkable continuum of gene expression states, with hundreds of genes maximally expressed in intermediate ...[more]
