Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Ingrid Raab
PROVIDER: E-MEXP-455 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Wick Nikolaus N Saharinen Pipsa P Saharinen Juha J Gurnhofer Elisabeth E Steiner Carl W CW Raab Ingrid I Stokic Dejan D Giovanoli Pietro P Buchsbaum Sabine S Burchard Aurea A Thurner Stefan S Alitalo Kari K Kerjaschki Dontscho D
Physiological genomics 20070101 2
The in vivo functions of lymphatic endothelial cells depend on their microenvironment, which cannot be fully reproduced in vitro. Because of technical limitations, gene expression in uncultured, "ex vivo" lymphatic endothelial cells has not been characterized at the molecular level. We combined tissue micropreparation and direct cell isolation with DNA chip experiments to identify 159 genes differentiating human lymphatic endothelial cells from blood vascular endothelial cells ex vivo. The same ...[more]