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Bromophycolides C-I from the Fijian red alga Callophycus serratus.

ABSTRACT: Bromophycolides C-I (1-7) were isolated from extracts of the Fijian red alga Callophycus serratus and identified by NMR and mass spectral techniques. These novel natural products share a carbon skeleton and biosynthetic origin with previously identified bromophycolides A (8) and B (9), which form a rare group of diterpene-benzoate macrolides. Bromophycolides C-I (1-7) displayed modest antineoplastic activity against a range of human tumor cell lines.

SUBMITTER: Kubanek J

PROVIDER: S-EPMC2528861 | biostudies-literature | 2006 May

REPOSITORIES: biostudies-literature

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Bromophycolides C-I from the Fijian red alga Callophycus serratus.

Kubanek Julia J Prusak Anne C AC Snell Terry W TW Giese Rachel A RA Fairchild Craig R CR Aalbersberg William W Hay Mark E ME

Journal of natural products 20060501 5

Bromophycolides C-I (1-7) were isolated from extracts of the Fijian red alga Callophycus serratus and identified by NMR and mass spectral techniques. These novel natural products share a carbon skeleton and biosynthetic origin with previously identified bromophycolides A (8) and B (9), which form a rare group of diterpene-benzoate macrolides. Bromophycolides C-I (1-7) displayed modest antineoplastic activity against a range of human tumor cell lines. ...[more]

PMID: 16724831

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