Unknown

Dataset Information

0

Bioactive bromophycolides R-U from the Fijian red alga Callophycus serratus.


ABSTRACT: Four new bromophycolides, R-U (1-4), were isolated from the Fijian red alga Callophycus serratus and were identified by 1D and 2D NMR and mass spectroscopic analyses. These compounds expand the known structural variety of diterpene-benzoate macrolides and exhibited modest cytotoxicity toward selected human cancer cell lines. Bromophycolide S (2) also showed submicromolar activity against the human malaria parasite Plasmodium falciparum.

SUBMITTER: Lin AS 

PROVIDER: S-EPMC3375676 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature

altmetric image

Publications

Bioactive bromophycolides R-U from the Fijian red alga Callophycus serratus.

Lin An-Shen AS   Stout E Paige EP   Prudhomme Jacques J   Le Roch Karine K   Fairchild Craig R CR   Franzblau Scott G SG   Aalbersberg William W   Hay Mark E ME   Kubanek Julia J  

Journal of natural products 20100201 2


Four new bromophycolides, R-U (1-4), were isolated from the Fijian red alga Callophycus serratus and were identified by 1D and 2D NMR and mass spectroscopic analyses. These compounds expand the known structural variety of diterpene-benzoate macrolides and exhibited modest cytotoxicity toward selected human cancer cell lines. Bromophycolide S (2) also showed submicromolar activity against the human malaria parasite Plasmodium falciparum. ...[more]

Similar Datasets

| S-EPMC2528861 | biostudies-literature
| S-EPMC2707147 | biostudies-literature
| S-EPMC3374858 | biostudies-literature
| S-EPMC3374863 | biostudies-literature
| S-EPMC3474338 | biostudies-literature
| S-EPMC5538829 | biostudies-literature
| S-EPMC2646105 | biostudies-literature
| S-EPMC2668242 | biostudies-literature
| S-EPMC8381616 | biostudies-literature
| S-EPMC3709513 | biostudies-literature