Ontology highlight
ABSTRACT:
SUBMITTER: Lin AS
PROVIDER: S-EPMC3375676 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Lin An-Shen AS Stout E Paige EP Prudhomme Jacques J Le Roch Karine K Fairchild Craig R CR Franzblau Scott G SG Aalbersberg William W Hay Mark E ME Kubanek Julia J
Journal of natural products 20100201 2
Four new bromophycolides, R-U (1-4), were isolated from the Fijian red alga Callophycus serratus and were identified by 1D and 2D NMR and mass spectroscopic analyses. These compounds expand the known structural variety of diterpene-benzoate macrolides and exhibited modest cytotoxicity toward selected human cancer cell lines. Bromophycolide S (2) also showed submicromolar activity against the human malaria parasite Plasmodium falciparum. ...[more]