Protein abundances following 24h of SPARK depletion in Toxoplasma gondii
Ontology highlight
ABSTRACT: Toxoplasma gondii is a ubiquitous eukaryotic pathogen. Apicomplexan parasites-the family to which T. gondii belongs-possess a divergent ortholog of mammalian PDK1. We have previously shown that this store potentiating/activating regulatory kinase (SPARK) is essential for T. gondii motility, invasion, and egress. Here, we conditionally depleted SPARK in live parasites for 24 hours to determine the impact of SPARK function on the parasite proteome.
INSTRUMENT(S): Orbitrap Exploris 480, FAIMS compensation voltage
ORGANISM(S): Toxoplasma Gondii Gt1
SUBMITTER: Alice Herneisen
LAB HEAD: Sebastian Lourido
PROVIDER: PXD040598 | Pride | 2024-07-12
REPOSITORIES: Pride
ACCESS DATA