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Protein abundances following 24h of SPARK depletion in Toxoplasma gondii

ABSTRACT: Toxoplasma gondii is a ubiquitous eukaryotic pathogen. Apicomplexan parasites-the family to which T. gondii belongs-possess a divergent ortholog of mammalian PDK1. We have previously shown that this store potentiating/activating regulatory kinase (SPARK) is essential for T. gondii motility, invasion, and egress. Here, we conditionally depleted SPARK in live parasites for 24 hours to determine the impact of SPARK function on the parasite proteome.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Toxoplasma Gondii Gt1

SUBMITTER: Alice Herneisen

LAB HEAD: Sebastian Lourido

PROVIDER: PXD040598 | Pride | 2024-07-12

REPOSITORIES: Pride

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			Action	DRS
	20211010_SPARK_WP_1.raw	Raw
	20211010_SPARK_WP_2.raw	Raw
	20211010_SPARK_WP_3.raw	Raw
	20211010_SPARK_WP_4.raw	Raw
	20211010_SPARK_WP_5.raw	Raw

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