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SPARKEL depletion time course proteome

ABSTRACT: Apicomplexan parasites are ubiquitous pathogens of humans. Toxoplasma gondii, a model apicomplexan, possesses a divergent ortholog of mammalian PDK1. This ortholog, TgSPARK, is essential for the ability of parasites to invade and exit their host. We discovered an interactor of SPARK, an elogin-like protein that we termed SPARKEL. Here, we conduct a quantitative mass spectrometry experiment to measure changes to the parasite proteome following 0, 3, 8, and 24 hours of conditional SPARKEL depletion.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Toxoplasma Gondii Gt1

SUBMITTER: Alice Herneisen

LAB HEAD: Sebastian Lourido

PROVIDER: PXD040635 | Pride | 2024-07-12

REPOSITORIES: Pride

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			Action	DRS
	20220213_tgALH274_depletion_proteome_1.raw	Raw
	20220213_tgALH274_depletion_proteome_1_CV4560.raw	Raw
	20220213_tgALH274_depletion_proteome_2.raw	Raw
	20220213_tgALH274_depletion_proteome_2_CV4560.raw	Raw
	20220213_tgALH274_depletion_proteome_3.raw	Raw

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