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Secondary metabolites from the soft coral Sinularia arborea.

ABSTRACT: Two new 13-hydroxycembrane diterpenoids, arbolides A (1) and B (2), along with a known trihydroxysteroid, crassarosterol A (3), were isolated from the soft coral Sinularia arborea. The structures of new cembranes 1 and 2 were elucidated by spectroscopic methods. Steroid 3 was found to exhibit cytotoxicity toward K562 and MOLT-4 leukemia.

SUBMITTER: Chen KH

PROVIDER: S-EPMC3801123 | biostudies-other | 2013 Sep

REPOSITORIES: biostudies-other

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Secondary metabolites from the soft coral Sinularia arborea.

Chen Kuan-Hua KH Dai Chang-Feng CF Lu Mei-Chin MC Li Jan-Jung JJ Chen Jih-Jung JJ Chang Yu-Chia YC Su Yin-Di YD Wang Wei-Hsien WH Sung Ping-Jyun PJ

Marine drugs 20130903 9

Two new 13-hydroxycembrane diterpenoids, arbolides A (1) and B (2), along with a known trihydroxysteroid, crassarosterol A (3), were isolated from the soft coral Sinularia arborea. The structures of new cembranes 1 and 2 were elucidated by spectroscopic methods. Steroid 3 was found to exhibit cytotoxicity toward K562 and MOLT-4 leukemia. ...[more]

PMID: 24005902

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